Jci The Il 23 Il 17 Axis In Inflammation
Interleukin 23 (IL23) is a heterodimeric cytokine of the IL12 superfamily that exhibits a proinflammatory role through its ability to contribute to the generation of Th17 cells Yet, it is unknown whether IL23 may alter the function of nonlymphoid cells The IL23/IL17 pathway has been reported to contribute to the pathogenesis of kidney disease characterized by chronic IL23R (Interleukin 23 Receptor) is a Protein Coding gene Diseases associated with IL23R include Inflammatory Bowel Disease 17 and Psoriasis 7 Among its related pathways are Th17 cell differentiation and Immune response IL23 signaling pathway
